Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835787 | 0.89 | HTR1A (0.48) | SCN1ASCN5ASCN9AALDH1A1DRD2 | |
| SCHEMBL11290166 | 0.78 | HTR1A (0.52) | KDM4EDRD2DRD4DRD3 | |
| SCHEMBL10836233 | 0.75 | HTR1A (0.56) | SCN1ASCN5ASCN9AMAPTDRD2 | |
| SCHEMBL10836259 | 0.75 | HTR1A (0.53) | SCN1ASCN5ASCN9ADRD2DRD4 | |
| SCHEMBL10836177 | 0.75 | S1PR1 (0.44) | DRD2DRD4DRD3 | |
| SCHEMBL10836497 | 0.75 | DRD2 (0.60) | DRD2 | |
| SCHEMBL10836380 | 0.75 | DRD2 (0.46) | SCN1ASCN5ASCN9ADRD2 | |
| Water SCHEMBL10836253 | 0.74 | S1PR1 (0.43) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL10837925 | 0.74 | S1PR1 (0.43) | DRD2DRD4DRD3 | |
| SCHEMBL10837230 | 0.74 | KDM4E (0.52) | SCN1ASCN5ASCN9AKDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619932-A | CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4567187-A | CENTRAL NERVOUS SYSTEM | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4460593-A | Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4455422-A | ANTIHISTAMINES, CNS CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |