Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291983 | 0.87 | ALOX15 (0.37) | RAB9AALDH1A1KDM4EAKR1C3KMT2A | |
| SCHEMBL11286758 | 0.81 | LMNA (0.38) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Benzene SCHEMBL11287558 | 0.79 | TSHR (0.56) | TOP1RAB9AALDH1A1GAATSHR | |
| SCHEMBL11283335 | 0.78 | TOP2A (0.36) | ALDH1A1MEN1KMT2AALOX15TRPV1 | |
| SCHEMBL11286258 | 0.77 | ALOX15 (0.41) | RAB9AALDH1A1GAATSHRKDM4E | |
| Anisole SCHEMBL11287389 | 0.77 | TSHR (0.47) | TOP1RAB9AALDH1A1GAATSHR | |
| SCHEMBL11290055 | 0.77 | ALOX15 (0.51) | RAB9AKMT2AALOX15NPC1TRPV1 | |
| SCHEMBL11290495 | 0.77 | ALOX15 (0.51) | RAB9AKMT2AALOX15NPC1TRPV1 | |
| SCHEMBL11277018 | 0.77 | ALOX15 (0.51) | RAB9AKMT2AALOX15NPC1TRPV1 | |
| SCHEMBL11283360 | 0.77 | ALOX15 (0.51) | RAB9AKMT2AALOX15NPC1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |