SCHEMBL1129352

SCHEMBL1129352

CCC(=O)c1cc(O)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.71
CA9 Q16790 6/20 0.59
CA12 O43570 5/20 0.59
CA1 P00915 5/20 0.59
CA2 P00918 5/20 0.59
CA7 P43166 5/20 0.59
CA14 Q9ULX7 5/20 0.59
ALOX5 P09917 1/20 0.57
PTGS2 P35354 1/20 0.57
HMGCR P04035 1/20 0.52
CHRNA7 P36544 3/20 0.51
NAAA Q02083 1/20 0.50
MEN1 O00255 1/20 0.50
CYP3A4 P08684 1/20 0.50
PTGS1 P23219 1/20 0.50
DRD3 P35462 1/20 0.50
KMT2A Q03164 1/20 0.50
HTT P42858 1/20 0.47
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29457562 1.00 HSP90AB1 (0.71) HSP90AB1CA9CA12CA1CA2
SCHEMBL9602694 0.84 ALDH1A1 (0.63) HSP90AB1CA9CA12CA1CA2
SCHEMBL481085 0.83 HSP90AB1 (1.00) HSP90AB1CA9CA12CA1CA2
SCHEMBL29457585 0.83 HSP90AB1 (1.00) HSP90AB1CA9CA12CA1CA2
SCHEMBL4706474 0.83 HSP90AB1 (1.00) HSP90AB1CA9CA12CA1CA2
SCHEMBL7769565 0.83 CA12 (0.61) HSP90AB1CA9CA12CA1CA2
SCHEMBL27963603 0.82 HSP90AB1 (0.70) HSP90AB1CA9CA12CA1CA2
SCHEMBL1305878 0.82 CSNK2A1 (0.62) HSP90AB1CA9CA12CA1CA2
SCHEMBL29368656 0.82 CSNK2A1 (0.62) HSP90AB1CA9CA12CA1CA2
SCHEMBL28049448 0.82 HSP90AB1 (0.96) HSP90AB1CA9CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11673997-B2 Work time to walk-on time ratio by adding a phenolic catalyst to polyaspartic flooring formulations COVESTRO LLC (US) 2023-06-13 US claimed
EP-4004076-A1 IMPROVED WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS Covestro LLC (US) 2022-06-01 EP claimed
CN-114144454-A Improved operating time to open-run time ratio by adding phenolic catalysts to polyaspartic flooring formulations 科思创有限公司 2022-03-04 CN claimed
WO-2021021801-A1 IMPROVED WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS COVESTRO LLC (US) 2021-02-04 WO claimed
EP-3404026-A1 PYRIMIDO-ISOQUINOLIN-QUINONE DERIVATIVE COMPOUNDS, AND PHARMACEUTICALLY ACCEPTABLE SALTS, ISOMERS AND TAUTOMERS THEREOF; PHARMACEUTICAL COMPOSITION; PREPARATION METHOD; AND USE THEREOF IN THE TREATMENT OF DISEASES CAUSED BY BACTERIA AND MULTIDRUG-RESISTANT BACTERIA Universidad De Chile (CL) 2018-11-21 EP claimed
CN-106854143-A A kind of synthetic method of hydroquinone derivative 湖南华腾制药有限公司 2017-06-16 CN claimed
EP-2374853-A1 Cyanate ester-based pressure sensitive adhesive CORNERSTONE RESEARCH GROUP, INC. (US) 2011-10-12 EP claimed
US-20100168279-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS HENKEL AG & CO. KGAA (DE) 2010-07-01 US claimed
US-20100137554-A1 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RESEARCH GROUP, INC. 2010-06-03 US claimed
EP-1979397-A4 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RES GROUP INC (US) 2009-04-08 EP claimed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
EP-1979397-A2 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2008-10-15 EP claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
WO-2008051241-A2 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2008-05-02 WO claimed
WO-2007114822-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-10-11 WO claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
CN-1882602-A Modulation and degradation of hyaluronan synthesis in the treatment of disease MEDITECH RES LTD (AU) 2006-12-20 CN claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA HSP90AB1 677/4885CA9 4380/4885CA12 4776/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA HSP90AB1 1306/4885CA9 1095/4885CA12 4408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.