Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | PTGIR | P43119 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801074 | 0.89 | KMT2A (0.62) | LMNASMN1; SMN2KMT2AALDH1A1PKM | |
| SCHEMBL12762430 | 0.88 | LMNA (0.59) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10528674 | 0.87 | KMT2A (0.64) | LMNASMN1; SMN2KMT2AALDH1A1PKM | |
| SCHEMBL27765368 | 0.87 | KMT2A (0.66) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7633148 | 0.87 | KMT2A (0.66) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18088853 | 0.87 | KMT2A (0.66) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16429579 | 0.87 | CES2 (0.69) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6482376 | 0.85 | ALDH1A1 (0.58) | LMNASMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL1546266 | 0.85 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12762443 | 0.84 | MAPT (0.54) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |