SCHEMBL6482376

SCHEMBL6482376

COc1ccc(C(=O)c2ccc(Sc3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
HPGD P15428 2/20 0.58
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
KMT2A Q03164 2/20 0.56
RAB9A P51151 2/20 0.56
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
PTGIR P43119 1/20 0.56
ACHE P22303 1/20 0.55
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
GAA P10253 2/20 0.51
ELANE P08246 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
KDM4E B2RXH2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757105 0.97 CES2 (0.62) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL29870046 0.97 CES2 (0.62) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL13134777 0.90 ALDH1A1 (0.51) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL13401274 0.88 CES2 (0.53) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL12757104 0.86 MAPT (0.56) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL21679403 0.86 MAPT (0.56) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL11295113 0.85 LMNA (0.55) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL6618691 0.85 CES2 (0.77) ALDH1A1HPGDCES2CES1KMT2A
Benzophenone SCHEMBL27935236 0.85 CES2 (0.77) ALDH1A1HPGDCES2CES1KMT2A
SCHEMBL50261 0.85 CES2 (0.77) ALDH1A1HPGDCES2CES1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6008269-A COMPRISING MICROCAPSULES WITH A TEMPERATURE-SENSITIVE COLOR CHANGE PROPERTY AND A BENZOPHENONE OR ACETOPHENONE TYPE PHOTOPOLYMERIZATION INITIATOR, WHEREIN SAID MICROCAPSULES CONTAIN NO ULTRAVIOLET ABSORBER AND SPECIFIC MEAN DIAMETER MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1999-12-28 US claimed
EP-4692072-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
WO-2024202087-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2024-10-03 WO disclosed
EP-1395615-B1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE BASF SE (DE) 2009-10-21 EP disclosed
US-6924251-B1 Substituted benzoylcyclohexandiones BAYER AKTIENGESELLSCHAFT (DE) 2005-08-02 US disclosed
US-6008269-A COMPRISING MICROCAPSULES WITH A TEMPERATURE-SENSITIVE COLOR CHANGE PROPERTY AND A BENZOPHENONE OR ACETOPHENONE TYPE PHOTOPOLYMERIZATION INITIATOR, WHEREIN SAID MICROCAPSULES CONTAIN NO ULTRAVIOLET ABSORBER AND SPECIFIC MEAN DIAMETER MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1999-12-28 US disclosed