Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297168 | 0.84 | MAPT (0.51) | MAOBRAB9AMEN1KMT2ALMNA | |
| SCHEMBL5579205 | 0.81 | RAB9A (0.42) | RAB9AMEN1KMT2ALMNAGAA | |
| SCHEMBL28388285 | 0.81 | PTPN1 (0.43) | MAOBRAB9AMEN1KMT2ALMNA | |
| SCHEMBL22770028 | 0.78 | MAPT (0.44) | MAOBCYP1A2ADORA2AADORA1RAB9A | |
| SCHEMBL20681466 | 0.77 | HDAC4 (0.50) | MAOBPTGS2RAB9AMEN1KMT2A | |
| SCHEMBL22769968 | 0.77 | BACE1 (0.49) | MAOBCYP1A2KMT2AMAPTKDM4E | |
| SCHEMBL14455176 | 0.76 | IDO1 (0.50) | MAOBBRD4CYP1A2PTGS2PTGS1 | |
| SCHEMBL28425347 | 0.74 | ALDH1A1 (0.54) | MAOBPTGS2PTGS1ADORA2AADORA1 | |
| SCHEMBL21253038 | 0.72 | PDK2 (0.40) | PTGS2PTGS1RAB9ANPC1 | |
| SCHEMBL21253173 | 0.72 | MAPT (0.38) | LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315749-A2 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2011-05-04 | — | — | EP | disclosed |
| WO-2009156735-A2 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-12-30 | — | — | WO | disclosed |