Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45432 | 0.80 | GABRA1 (0.53) | GABRA1GABRB2AKR1B1MTNR1ASRD5A1 | |
| SCHEMBL9297409 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2AKR1B1MTNR1ASRD5A1 | |
| SCHEMBL1194767 | 0.78 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1MTNR1AHSPA5 | |
| SCHEMBL9027584 | 0.78 | MTNR1A (0.46) | GABRA1GABRB2AKR1B1MTNR1ASRD5A1 | |
| SCHEMBL323547 | 0.78 | XDH (0.54) | GABRA1GABRB2AKR1B1MTNR1ASRD5A1 | |
| 2-Allylphenol SCHEMBL29381085 | 0.76 | GABRA1 (0.57) | GABRA1GABRB2TAAR1AKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL31591833 | 0.76 | GABRA1 (0.57) | GABRA1GABRB2TAAR1AKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL160157 | 0.76 | GABRA1 (0.57) | GABRA1GABRB2TAAR1AKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL5489147 | 0.76 | GABRA1 (0.57) | GABRA1GABRB2TAAR1AKR1B1HSPA5 | |
| Hydrogen Sulfide SCHEMBL6721312 | 0.75 | XDH (0.52) | GABRA1GABRB2AKR1B1MTNR1ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321343-A | Polyisobutylene/phenol polymers treated with diisocyanates and poly(oxyalkylene)polyols | W. R. GRACE & CO. (US) | 1982-03-23 | — | — | US | disclosed |
| US-4107144-A | Phenolic antioxidants with polymer tails | CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) | 1978-08-15 | — | — | US | disclosed |