Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946753 | 1.00 | GPR84 (0.44) | GPR84SMN1; SMN2MAPTTP53DHFR | |
| SCHEMBL4814536 | 0.97 | GPR84 (0.42) | GPR84SMN1; SMN2MAPTTP53DHFR | |
| SCHEMBL6618330 | 0.94 | GSK3B (0.44) | GPR84SMN1; SMN2MAPTTP53TLR8 | |
| Ammonia Solution, Strong SCHEMBL27564785 | 0.92 | GSK3B (0.43) | GPR84SMN1; SMN2MAPTTP53TLR8 | |
| Benzylamine SCHEMBL28750130 | 0.91 | TLR8 (0.42) | GPR84SMN1; SMN2MAPTTP53DHFR | |
| SCHEMBL1917870 | 0.87 | ADORA3 (0.50) | SMN1; SMN2MAPTTP53TLR8NPC1 | |
| SCHEMBL27815847 | 0.86 | HSD11B1 (0.50) | GPR84MAPTTP53KCNH2ALDH1A1 | |
| SCHEMBL27835295 | 0.86 | HSD11B1 (0.50) | GPR84MAPTTP53KCNH2ALDH1A1 | |
| SCHEMBL1927324 | 0.84 | MAOA (0.42) | MAPTTLR8 | |
| Benzylamine SCHEMBL27571278 | 0.84 | TLR8 (0.39) | SMN1; SMN2TLR8HSD11B1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322459-A | Epoxy derived resins containing amino or mercapto substituted azole functionality and compositions containing same | PPG INDUSTRIES, INC. (US) | 1982-03-30 | — | — | US | disclosed |