SCHEMBL11297581

SCHEMBL11297581

CCOC(=O)C(C)=COC(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
GLO1 Q04760 1/20 0.44
NPSR1 Q6W5P4 2/20 0.39
ALDH1A1 P00352 5/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 1/20 0.36
TRPA1 O75762 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
S1PR4 O95977 1/20 0.35
S1PR1 P21453 1/20 0.35
MAPK1 P28482 1/20 0.35
TSHR P16473 1/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8510420 0.85 HCAR2 (0.36) ALOX15NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL6935316 0.83 ALDH1A1 (0.48) ALOX15GLO1NPSR1ALDH1A1LMNA
SCHEMBL27734236 0.80 GLO1 (0.38) ALOX15GLO1NPSR1ALDH1A1LMNA
SCHEMBL27759645 0.80 HCAR2 (0.45) ALOX15GLO1NPSR1ALDH1A1LMNA
SCHEMBL11576487 0.79 MAPT (0.39) ALOX15ALDH1A1HSD17B10MAPTTSHR
SCHEMBL15452917 0.79 GLO1 (0.47) ALOX15GLO1NPSR1ALDH1A1LMNA
SCHEMBL19447665 0.79 GLO1 (0.50) ALOX15GLO1NPSR1ALDH1A1LMNA
SCHEMBL322511 0.79 GLO1 (0.50) ALOX15GLO1NPSR1ALDH1A1LMNA
SCHEMBL222772 0.79 GLO1 (0.50) ALOX15GLO1NPSR1ALDH1A1LMNA
SCHEMBL20815351 0.78 THRB (0.44) GLO1NPSR1ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10793679-B2 Radically curable organosiloxane graft polyvinyl alcohol polymer and process for producing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-06 US disclosed
EP-3527598-B1 RADICALLY CURABLE ORGANOSILOXANE GRAFT POLYVINYL ALCOHOL POLYMER AND PROCESS FOR PRODUCING SAME SHINETSU CHEMICAL CO (JP) 2020-09-16 EP disclosed
US-20190256663-A1 RADICALLY CURABLE ORGANOSILOXANE GRAFT POLYVINYL ALCOHOL POLYMER AND PROCESS FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-08-22 US disclosed
EP-3527598-A1 RADICALLY CURABLE ORGANOSILOXANE GRAFT POLYVINYL ALCOHOL POLYMER AND PROCESS FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2019-08-21 EP disclosed
EP-0003741-B1 RADIATION CURABLE PRESSURE SENSITIVE ADHESIVE AND PROCESS OF PREPARATION THEREOF UNION CARBIDE CORPORATION (US) 1982-12-22 EP disclosed