Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 16/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296776 | 0.84 | REN (0.33) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL11300982 | 0.82 | HDAC8 (0.36) | HDAC8 | |
| SCHEMBL11297857 | 0.81 | REN (0.39) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL11302453 | 0.81 | HDAC8 (0.37) | HDAC8MEN1KMT2A | |
| SCHEMBL11294066 | 0.79 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL11302460 | 0.77 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL11299184 | 0.77 | HDAC8 (0.42) | HDAC8 | |
| SCHEMBL11295563 | 0.77 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL11304921 | 0.76 | HDAC8 (0.46) | HDAC8MEN1KMT2A | |
| SCHEMBL11300475 | 0.75 | HDAC8 (0.34) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |