Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298342 | 0.86 | ACHE (0.43) | HDAC8ACHECTSLNR1H4NPSR1 | |
| SCHEMBL11302453 | 0.84 | HDAC8 (0.37) | HDAC8NPSR1POLBHPGD | |
| SCHEMBL11296820 | 0.82 | PPARG (0.41) | PPARG | |
| SCHEMBL11297857 | 0.77 | REN (0.39) | — | |
| SCHEMBL11305331 | 0.77 | HDAC8 (0.35) | HDAC8 | |
| SCHEMBL11298187 | 0.77 | TAS1R3 (0.40) | NPSR1POLBHPGD | |
| SCHEMBL11299074 | 0.74 | PPARG (0.41) | PPARGHPGD | |
| SCHEMBL11304921 | 0.74 | HDAC8 (0.46) | HDAC8HDAC6POLBHDAC11HDAC3 | |
| SCHEMBL11300475 | 0.73 | HDAC8 (0.34) | HDAC8 | |
| SCHEMBL11294344 | 0.73 | CYP4F2 (0.43) | PPARGHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |