Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 5/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652275 | 0.80 | NMT2 (0.43) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL1711732 | 0.78 | CPB2 (0.47) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL1711325 | 0.78 | CPB2 (0.47) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL1711738 | 0.78 | CPB2 (0.47) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL30284335 | 0.78 | CPB2 (0.45) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL1711321 | 0.78 | CPB2 (0.47) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL386663 | 0.78 | PDF (0.61) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL547491 | 0.78 | PDF (0.61) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| SCHEMBL27750016 | 0.78 | PDF (0.61) | ERAP2LNPEPERAP1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL3482618 | 0.77 | PDF (0.60) | ERAP2LNPEPERAP1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038357-A4 | HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS. | UNIV ILLINOIS (US) | 1982-03-22 | — | — | EP | disclosed |
| EP-0038357-A1 | HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS | University of Illinois Foundation (US) | 1981-10-28 | — | — | EP | disclosed |
| WO-1981001145-A1 | HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS | UNIV ILLINOIS (US) | 1981-04-30 | — | — | WO | disclosed |