Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250780 | 0.93 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL16386431 | 0.90 | LMNA (0.50) | ALDH1A1LMNANPC1RAB9AFFAR1 | |
| SCHEMBL8187637 | 0.90 | HDAC1 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8168492 | 0.80 | HDAC3 (0.59) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL11176136 | 0.78 | PLAAT3 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL7753254 | 0.77 | ESR1 (0.56) | HDAC2HDAC8SLC6A3ALDH1A1LMNA | |
| SCHEMBL11178054 | 0.77 | FFAR1 (0.47) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL11179937 | 0.77 | TDP1 (0.61) | SMN1; SMN2ALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL11174125 | 0.77 | FFAR1 (0.51) | ALDH1A1FFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL23003726 | 0.76 | LMNA (0.56) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026846-B1 | SUBSTITUTED FULVALENOPHANE DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4298751-A | Cyclically substituted fulvalenophanes | BASF AKTIENGESELLSCHAFT (DE) | 1981-11-03 | — | — | US | disclosed |
| EP-0026846-A1 | Substituted fulvalenophane derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |