Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298948 | 0.93 | HDAC1 (0.48) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL16386431 | 0.84 | LMNA (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL8187637 | 0.83 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8171842 | 0.79 | HDAC3 (0.66) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11176136 | 0.77 | PLAAT3 (0.50) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9679405 | 0.77 | HDAC1 (0.49) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL13443080 | 0.76 | MAPT (0.61) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4886613 | 0.76 | MAPT (0.73) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL6261613 | 0.75 | FAAH (0.58) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL11178054 | 0.75 | FFAR1 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026846-B1 | SUBSTITUTED FULVALENOPHANE DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4298751-A | Cyclically substituted fulvalenophanes | BASF AKTIENGESELLSCHAFT (DE) | 1981-11-03 | — | — | US | disclosed |
| EP-0026846-A1 | Substituted fulvalenophane derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |