SCHEMBL11299077

SCHEMBL11299077

C=Cc1ccc(Oc2ccccc2C=C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.48
KMT2A Q03164 3/20 0.48
GAA P10253 2/20 0.48
ALDH1A1 P00352 9/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
HPGD P15428 5/20 0.44
HTT P42858 5/20 0.44
TSHR P16473 1/20 0.43
MAPT P10636 3/20 0.42
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MAP2K1 Q02750 1/20 0.42
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
APEX1 P27695 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530440 1.00 LMNA (0.48) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL298766 0.86 LMNA (0.64) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL30618855 0.86 LMNA (0.64) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL12516805 0.83 ALDH1A1 (0.69) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL6033685 0.83 HTT (0.63) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL6033676 0.83 LMNA (0.63) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL297297 0.81 ALDH1A1 (0.48) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL27584670 0.80 CYP1A2 (0.51) LMNAKMT2AALDH1A1CYP1A2CYP2C9
SCHEMBL18656991 0.80 LMNA (0.45) LMNAKMT2AGAAALDH1A1CYP1A2
SCHEMBL19296412 0.79 ALDH1A1 (0.70) LMNAKMT2AGAAALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12129409-B2 Reactive silicone composition and cured product thereof NISSAN CHEMICAL CORPORATION (JP) 2024-10-29 US disclosed
US-20220010176-A1 REACTIVE SILICONE COMPOSITION AND CURED PRODUCT THEREOF NISSAN CHEMICAL CORPORATION (JP) 2022-01-13 US disclosed
EP-3885381-A1 REACTIVE SILICONE COMPOSITION AND CURED PRODUCT OF SAME Nissan Chemical Corporation (JP) 2021-09-29 EP disclosed
CN-109071731-B Polymerizable composition containing reactive phenanthrene ring-containing silsesquioxane compound 日产化学株式会社 2021-08-13 CN disclosed
CN-113166343-A Reactive silicone composition and cured product thereof 日产化学株式会社 2021-07-23 CN disclosed
CN-109196008-B Reactive polysiloxane and polymerizable composition containing same 日产化学株式会社 2021-07-06 CN disclosed
US-10899891-B2 Reactive polysiloxane and polymerizable composition comprising same NISSAN CHEMICAL CORPORATION (JP) 2021-01-26 US disclosed
EP-2665762-B1 POLYMERIZABLE COMPOSITIONS, CURED PRODUCTS OBTAINED THEREWITH, AND USE OF THESE MATERIALS FRAUNHOFER GES FORSCHUNG (DE) 2020-12-02 EP disclosed
US-10787535-B2 Polymerizable composition containing reactive silsesquioxane compound containing phenanthrene ring NISSAN CHEMICAL CORPORATION (JP) 2020-09-29 US disclosed
EP-3466994-B1 REACTIVE POLYSILOXANE AND POLYMERIZABLE COMPOSITION CONTAINING SAME NISSAN CHEMICAL CORP (JP) 2020-09-16 EP disclosed
EP-3444284-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND CONTAINING PHENANTHRENE RING Nissan Chemical Corporation (JP) 2019-02-20 EP disclosed
US-20180305488-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-25 US disclosed
EP-3373051-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-09-12 EP disclosed
EP-3367144-A1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-08-29 EP disclosed
EP-3327049-A1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
US-20160369062-A1 POLYMERIZABLE COMPOSITIONS, CURED PRODUCTS OBTAINED THEREWITH, AND USE OF THESE MATERIALS NISSAN CHEMICAL IND LTD (JP) 2016-12-22 US disclosed
US-9434818-B2 Polymerizable compositions, cured products obtained therewith, and use of these materials Fraundhofer-Gesellschaft zur Foerderung der angewandter Forschung e.V. (DE) 2016-09-06 US disclosed
US-20140051821-A1 POLYMERIZABLE COMPOSITIONS, CURED PRODUCTS OBTAINED THEREWITH, AND USE OF THESE MATERIALS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-02-20 US disclosed
EP-2665762-A1 POLYMERIZABLE COMPOSITIONS, CURED PRODUCTS OBTAINED THEREWITH, AND USE OF THESE MATERIALS Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. (DE) 2013-11-27 EP disclosed
WO-2012097836-A1 POLYMERIZABLE COMPOSITIONS, CURED PRODUCTS OBTAINED THEREWITH, AND USE OF THESE MATERIALS FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER... (DE) 2012-07-26 WO disclosed