Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292728 | 0.86 | GPR84 (0.38) | EGFRTAAR1ADORA2AADORA1GPR84 | |
| SCHEMBL8958035 | 0.84 | TAAR1 (0.44) | ALDH1A1P2RX7MEN1KMT2AGAA | |
| SCHEMBL10957691 | 0.83 | AR (0.38) | ARADORA2AADORA1 | |
| SCHEMBL2943483 | 0.81 | ADRA2A (0.55) | ALDH1A1HPGDGAASMN1; SMN2TAAR1 | |
| SCHEMBL11298066 | 0.80 | LTA4H (0.38) | EGFRARALDH1A1P2RX7HPGD | |
| SCHEMBL11288882 | 0.80 | TAAR1 (0.54) | ARUSP2TAAR1ADORA2AADORA1 | |
| SCHEMBL316101 | 0.79 | TAAR1 (0.48) | KMT2AGAATAAR1ADORA2AADORA1 | |
| SCHEMBL10770458 | 0.78 | CHEK2 (0.43) | EGFRARALDH1A1HPGDMEN1 | |
| SCHEMBL10951835 | 0.77 | ALDH1A1 (0.45) | ARALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11291266 | 0.75 | HTR2A (0.33) | SMN1; SMN2TAAR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |