Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353285 | 0.86 | EPHX1 (0.47) | HPGDELANEEPHX1KMT2AATM | |
| SCHEMBL6445938 | 0.75 | HPGD (0.49) | LMNAMAPK1HPGDELANEMEN1 | |
| SCHEMBL147468 | 0.75 | ELANE (0.47) | HPGDELANEATMTDP1L3MBTL1 | |
| SCHEMBL732424 | 0.75 | ELANE (0.47) | HPGDELANEKMT2AATMTDP1 | |
| Mandelic Acid SCHEMBL11303728 | 0.75 | LMNA (0.72) | LMNAMAPK1HPGDCES2CES1 | |
| SCHEMBL28268633 | 0.75 | ELANE (0.42) | HPGDELANEATMTDP1L3MBTL1 | |
| Mandelic Acid SCHEMBL281913 | 0.74 | LMNA (0.78) | LMNAMAPK1HPGDCES2CES1 | |
| SCHEMBL9998913 | 0.74 | THRA (0.44) | ELANEEPHX1ATMTDP1L3MBTL1 | |
| SCHEMBL10707039 | 0.74 | ELANE (0.55) | LMNAMAPK1HPGDELANEMEN1 | |
| SCHEMBL4286692 | 0.74 | NOS3 (0.52) | LMNAELANEMEN1KMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098560-A2 | PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST | MSN LABORATORIES LIMITED (IN) | 2012-07-26 | — | — | WO | disclosed |