Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.66 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NQO2 | P16083 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2795344 | 0.85 | MTNR1A (0.49) | MTNR1AMTNR1BSMN1; SMN2KMT2A | |
| SCHEMBL30080255 | 0.85 | MTNR1A (0.53) | MTNR1AMTNR1BHTR2BHTR2CSMN1; SMN2 | |
| SCHEMBL18183442 | 0.84 | MTNR1B (0.84) | MTNR1AMTNR1BHTR2BHTR2C | |
| SCHEMBL3152901 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1BSMN1; SMN2NQO2KDM4E | |
| SCHEMBL13673154 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BHTR2BHTR2CSMN1; SMN2 | |
| SCHEMBL534135 | 0.79 | SMN1; SMN2 (0.70) | MTNR1AMTNR1BSMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL31627780 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BNOTUM | |
| SCHEMBL16294203 | 0.79 | POLB (0.48) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL534533 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BNOTUM | |
| SCHEMBL7551792 | 0.79 | ADRA1A (0.48) | HTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56128756-A | — | — | None | — | — | JP | disclosed |
| JP-S56128756-A | PREPARATION OF INDOLE DERIVATIVE | SENDAI FUKUSOKAN KAGAKU KENKYUSHO | 1981-10-08 | — | — | JP | disclosed |