Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23809161 | 0.82 | WDR5 (0.59) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL14150964 | 0.77 | WDR5 (0.53) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL7539671 | 0.74 | WDR5 (0.49) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL28789417 | 0.72 | WDR5 (0.54) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL6539256 | 0.70 | WDR5 (0.61) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL5860743 | 0.70 | WDR5 (0.51) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL248146 | 0.70 | WDR5 (0.66) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL3370101 | 0.70 | WDR5 (0.66) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL9807649 | 0.69 | NCEH1 (0.51) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL895573 | 0.69 | WDR5 (1.00) | WDR5LDHANR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4291058-A | CONTAINING A TRIPLE BOND, USED TO CONTROL INSECTS AND ACARIDS | HOFFMANN-LA ROCHE INC. (US) | 1981-09-22 | — | — | US | disclosed |