SCHEMBL113103

SCHEMBL113103

Clc1nc(Cl)nc(Nc2ccccc2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 4/20 1.00
MAPT P10636 3/20 0.91
MEN1 O00255 2/20 0.91
KMT2A Q03164 2/20 0.91
MAPK1 P28482 1/20 0.91
LMNA P02545 1/20 0.75
NPC1 O15118 1/20 0.68
RAB9A P51151 1/20 0.68
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CA9 Q16790 2/20 0.62
TSHR P16473 1/20 0.59
TXN P10599 1/20 0.58
KDM4E B2RXH2 2/20 0.57
GAA P10253 1/20 0.57
CA14 Q9ULX7 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
KCNH3 Q9ULD8 3/20 0.52
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21655135 1.00 NFKB1 (1.00) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL23643402 0.96 NFKB1 (0.92) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL1923883 0.95 MAPT (1.00) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL11837292 0.88 NFKB1 (0.78) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL11785940 0.88 NFKB1 (0.78) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL3499751 0.88 MAPT (0.85) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL11885185 0.86 LMNA (1.00) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL8909557 0.86 MAPT (0.81) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL8908232 0.86 NFKB1 (0.75) NFKB1MAPTMEN1KMT2AMAPK1
SCHEMBL27617353 0.86 MAPT (0.81) NFKB1MAPTMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658616-B1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS FRAUNHOFER GES FORSCHUNG (DE) 2025-10-22 EP claimed
CN-110945066-B Halogen-free sulfonate and/or sulfinate esters as flame retardants, flame retardant synergists and free radical generators in plastics 弗劳恩霍弗应用研究促进协会 2022-10-14 CN claimed
CN-110945066-A Halogen-free sulfonate and/or sulfinate esters as flame retardants, flame retardant synergists and free radical generators in plastics 弗劳恩霍弗应用研究促进协会 2020-03-31 CN claimed
EP-2638179-B1 NON METAL TANNING STAHL INT BV (NL) 2014-11-26 EP claimed
EP-2481730-B1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES LLC (US) 2013-12-18 EP claimed
EP-2481731-B1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES LLC (US) 2013-10-23 EP claimed
EP-2197857-B1 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2013-03-06 EP claimed
EP-2481730-A1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones Dow AgroSciences LLC (US) 2012-08-01 EP claimed
EP-2481731-A1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones Dow AgroSciences LLC (US) 2012-08-01 EP claimed
US-8188273-B2 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES, LLC. (US) 2012-05-29 US claimed
US-8067588-B2 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES LLC (US) 2011-11-29 US claimed
EP-2197857-A2 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES Dow AgroSciences LLC (US) 2010-06-23 EP claimed
WO-2009048750-A2 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2009-04-16 WO claimed
US-20090093481-A1 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2009-04-09 US claimed
US-20030209491-A1 Simulated activity of protein a displayed by ligands attached to a cellulose bead surface ACCURATE POLYMERS, LTD. 2003-11-13 US claimed
EP-0946093-B1 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO SPA (IT) 2002-08-28 EP claimed
US-20010045384-A1 Simulated activity of protein a displayed by ligands attached to a cellulose bead surface ACCURATE POLYMERS, LTD. 2001-11-29 US claimed
US-6228885-B1 Fungicidal compositions based on (N-phenylacetyl-N-2,6-XYLYL)methyl alaninate ISAGRO S.P.A. (IT) 2001-05-08 US claimed
EP-0380017-A2 A process for the preparation of triazinic polymers HIMONT ITALIA S.r.l. (IT) 1990-08-01 EP claimed
US-4563189-A WOOL AND COTTON WOOL DEVELOPMENT INTERNATIONAL LTD. (GB) 1986-01-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090093481-A1 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES HELZ, API5, CRYZ NFKB1 2863/4885MAPT 2948/4885MEN1 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.