Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318018 | 1.00 | NFKB1 (0.54) | NFKB1MAOBP4HBABCG2LMNA | |
| SCHEMBL11318023 | 1.00 | NFKB1 (0.54) | NFKB1MAOBP4HBABCG2LMNA | |
| SCHEMBL11390679 | 0.87 | ALDH1A1 (0.39) | NFKB1MAOBP4HBABCG2LMNA | |
| SCHEMBL11390672 | 0.87 | ALDH1A1 (0.39) | NFKB1MAOBP4HBABCG2LMNA | |
| SCHEMBL11390669 | 0.87 | ALDH1A1 (0.39) | NFKB1MAOBP4HBABCG2LMNA | |
| SCHEMBL11316938 | 0.80 | NFE2L2 (0.47) | MAOBMAPTNFE2L2SMN1; SMN2 | |
| SCHEMBL11316941 | 0.80 | NFE2L2 (0.47) | MAOBMAPTNFE2L2SMN1; SMN2 | |
| SCHEMBL11316940 | 0.80 | NFE2L2 (0.47) | MAOBMAPTNFE2L2SMN1; SMN2 | |
| SCHEMBL9967712 | 0.77 | NFKB1 (0.53) | NFKB1MAOBP4HBABCG2LMNA | |
| SCHEMBL11311798 | 0.77 | MAPT (0.45) | NFKB1MAOBLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267359-A | Novel carboxylic acid esters | ZOECON CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
| US-4248875-A | INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4229368-A | Esters and thiolesters of unsaturated acids | ZOECON CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4204071-A | 4-Aryl-3-butenoic acids and lower alkyl esters | ZOECON CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |