Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 3/20 | 0.39 |
| ▸ | MC5R | P33032 | 3/20 | 0.39 |
| ▸ | MC3R | P41968 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318737 | 0.97 | TMEM97 (0.42) | PDE6DFOLH1TMEM97SIGMAR1GLP1R | |
| SCHEMBL11328953 | 0.89 | HDAC6 (0.44) | HDAC1 | |
| SCHEMBL11327056 | 0.87 | POLB (0.43) | — | |
| SCHEMBL11314879 | 0.83 | OPRD1 (0.43) | PDE6DFOLH1TMEM97SIGMAR1KDM4A | |
| SCHEMBL11320955 | 0.81 | OPRD1 (0.44) | FOLH1TMEM97SIGMAR1GLP1RGCGR | |
| SCHEMBL11326306 | 0.79 | CCKBR (0.41) | PDE6DBCHEACHE | |
| SCHEMBL11224728 | 0.79 | TMEM97 (0.49) | TMEM97SIGMAR1HDAC1 | |
| SCHEMBL11224743 | 0.78 | POLB (0.40) | PDE6DFOLH1GCGRHDAC1 | |
| SCHEMBL11320468 | 0.77 | AGER (0.50) | TMEM97SIGMAR1HDAC1 | |
| SCHEMBL11322274 | 0.77 | ALOX5 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |