SCHEMBL11321069

SCHEMBL11321069

O=C(Nc1ccccc1)OCOC(=O)Nc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
TSHR P16473 2/20 0.62
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
RECQL P46063 1/20 0.61
LMNA P02545 3/20 0.57
NPSR1 Q6W5P4 2/20 0.57
HPGD P15428 1/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
POLB P06746 1/20 0.54
TP53 P04637 2/20 0.54
EPHX1 P07099 1/20 0.54
EPHX2 P34913 1/20 0.54
CDK9 P50750 1/20 0.54
CLK4 Q9HAZ1 1/20 0.54
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL11339278 0.92 RAB9A (0.57) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL28632759 0.88 LMNA (0.56) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL14472485 0.86 RAB9A (0.50) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL25437171 0.85 NPC1 (0.61) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL25436393 0.85 NPC1 (0.61) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL8827353 0.84 SMN1; SMN2 (0.61) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL10597471 0.83 RAB9A (0.77) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL482922 0.83 NPC1 (0.59) NPC1RAB9ASMN1; SMN2TSHRMEN1
Ethyl Phenylcarbamate SCHEMBL264865 0.83 RAB9A (0.75) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL6588494 0.83 NPC1 (0.59) NPC1RAB9ASMN1; SMN2TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4287132-A THE IMPROVED PROCESS WHEREIN THE POLYCARBAMATE IS DISTILLED, A POLAR SOLVENT IS ADDED TO THE RESIDUE, AND THE RESULTING SOLUTION IS CRYSTALLIZED ATLANTIC RICHFIELD COMPANY (US) 1981-09-01 US claimed
US-10392484-B2 Cellulose acylate film, production method of cellulose acylate film, stack, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-08-27 US disclosed
US-10040754-B2 Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2018-08-07 US disclosed
US-20170088681-A1 CELLULOSE ACYLATE FILM, PRODUCTION METHOD OF CELLULOSE ACYLATE FILM, STACK, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-03-30 US disclosed
US-20170088681-A1 CELLULOSE ACYLATE FILM, PRODUCTION METHOD OF CELLULOSE ACYLATE FILM, STACK, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-03-30 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160060405-A1 POLYMER FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-20150361036-A1 CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed
US-4307029-A Process for preparing polymethylene-polyphenyl polyisocyanates MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1981-12-22 US disclosed
US-4287132-A THE IMPROVED PROCESS WHEREIN THE POLYCARBAMATE IS DISTILLED, A POLAR SOLVENT IS ADDED TO THE RESIDUE, AND THE RESULTING SOLUTION IS CRYSTALLIZED ATLANTIC RICHFIELD COMPANY (US) 1981-09-01 US disclosed
US-4287132-A THE IMPROVED PROCESS WHEREIN THE POLYCARBAMATE IS DISTILLED, A POLAR SOLVENT IS ADDED TO THE RESIDUE, AND THE RESULTING SOLUTION IS CRYSTALLIZED ATLANTIC RICHFIELD COMPANY (US) 1981-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040754-B2 Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device NR1D1, NR1H2, NR1D2 NPC1 456/4885RAB9A 4375/4885SMN1; SMN2 3280/4885
US-20150361036-A1 CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE NR1D1, NR1H2, NR1D2 NPC1 456/4885RAB9A 4375/4885SMN1; SMN2 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.