Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791580 | 0.80 | KCNH2 (0.36) | TLR8MAPTKDM4EKCNH2HPGD | |
| SCHEMBL9284521 | 0.77 | PKM (0.42) | TLR8 | |
| SCHEMBL24954185 | 0.75 | KCNH2 (0.37) | TLR8MAPTKDM4EKCNH2HPGD | |
| SCHEMBL27429022 | 0.70 | MEN1 (0.39) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL12496377 | 0.68 | LMNA (0.39) | TLR8HPGDALDH1A1HSD17B10NPC1 | |
| SCHEMBL11019463 | 0.68 | RAB9A (0.55) | MAPTKDM4EKCNH2HPGDALDH1A1 | |
| SCHEMBL4262711 | 0.67 | HPGD (0.43) | MAPTKDM4EHPGDALDH1A1HSD17B10 | |
| Carbon Monoxide SCHEMBL6349233 | 0.67 | TRPM8 (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5749103 | 0.67 | KCNH2 (0.41) | TLR8MAPTKCNH2 | |
| SCHEMBL30042167 | 0.67 | TLR8 (0.46) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256738-A | BACTERICIDES, PYRIMIDINYL, QUINAZOLINYL | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-17 | — | — | US | disclosed |