Carbon Monoxide

Carbon Monoxide

SCHEMBL6349233

CCCCCc1cnc(-c2ccccn2)nc1Cl.[C]=O.[C]=O.[C]=O.[Re]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.47
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP19A1 P11511 1/20 0.40
METAP1 P53582 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
PPP1CA P62136 2/20 0.39
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13471428 0.83 TRPM8 (0.60) TRPM8CYP1A2CYP2C9CYP2C19METAP1
SCHEMBL6347377 0.73 RARB (0.48) CYP1A2CYP2C9CYP2C19CYP2D6CYP19A1
SCHEMBL586654 0.71 KCNH2 (0.49) TRPM8CYP1A2CYP2C9CYP2C19CYP2D6
SCHEMBL3628279 0.70 TP53 (0.49) CYP1A2CYP2C9CYP2C19CYP2D6CYP19A1
SCHEMBL9284521 0.70 PKM (0.42)
SCHEMBL1442705 0.69 L3MBTL1 (0.56) TRPM8CYP1A2CYP2C9CYP2C19METAP1
SCHEMBL11019463 0.69 RAB9A (0.55) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL791580 0.69 KCNH2 (0.36) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL10270653 0.69 TRPM8 (0.60) TRPM8SMN1; SMN2PPP1CALMNAALDH1A1
SCHEMBL21565085 0.68 LIPG (0.49) CYP1A2CYP2C9CYP2C19CYP2D6CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6929873-B2 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-08-16 US disclosed
US-20040013905-A1 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2004-01-22 US disclosed