Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333866 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TP53NPC1LMNA | |
| SCHEMBL11337145 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TP53NPC1LMNA | |
| SCHEMBL11335502 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL18700925 | 0.82 | PRKAB2 (0.48) | SMN1; SMN2ALDH1A1TP53PKMNPSR1 | |
| Hydrochloric Acid SCHEMBL27732240 | 0.81 | PRKAB2 (0.47) | SMN1; SMN2ALDH1A1TP53PKMNPSR1 | |
| SCHEMBL1817972 | 0.80 | TRPV4 (0.53) | SMN1; SMN2ALDH1A1TP53PKMNPSR1 | |
| SCHEMBL11334756 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TP53NPC1LMNA | |
| SCHEMBL11327832 | 0.79 | L3MBTL1 (0.58) | SMN1; SMN2ALDH1A1TP53LMNAMAPT | |
| SCHEMBL21800161 | 0.79 | CA2 (0.49) | SMN1; SMN2ALDH1A1PKMNPSR1 | |
| SCHEMBL9559150 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TP53NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260552-A | INSECTICIDES, HERBICIDES | UNIROYAL, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4160846-A | Method for controlling insects with tetrasubstituted organotin compounds | UNIROYAL, INC. (US) | 1979-07-10 | — | — | US | disclosed |