Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 5/20 | 0.37 |
| ▸ | TEC | P42680 | 1/20 | 0.37 |
| ▸ | TXK | P42681 | 1/20 | 0.37 |
| ▸ | BMX | P51813 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334908 | 0.78 | ALDH1A1 (0.52) | HDAC1HDAC2PTPN1MEN1KMT2A | |
| SCHEMBL16096123 | 0.76 | TGM2 (0.47) | TGM2JAK3BTKTECTXK | |
| SCHEMBL29416535 | 0.75 | TGM2 (0.55) | HDAC4TGM2HDAC1HDAC2PTPN1 | |
| SCHEMBL2316517 | 0.75 | TGM2 (0.55) | HDAC4TGM2HDAC1HDAC2PTPN1 | |
| SCHEMBL21322422 | 0.75 | S100B (0.46) | HDAC4MEF2DHDAC1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL29278808 | 0.74 | TGM2 (0.53) | HDAC4TGM2HDAC1HDAC2PTPN1 | |
| SCHEMBL10024764 | 0.73 | PTPN1 (0.51) | TGM2BTKPTPN1PTPN11NPC1 | |
| SCHEMBL7655945 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL17931860 | 0.70 | TGM2 (0.46) | TGM2JAK3BTKTECTXK | |
| SCHEMBL7178423 | 0.69 | EGFR (0.52) | HDAC4TGM2HDAC1HDAC2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243584-A | Monoazo dyestuffs containing diazo component substituted by disulfimide and trifluoromethyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4159265-A | Phenylazopyrazolo dyestuffs including disulfimide substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |
| US-3978039-A | POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-24 | — | — | US | disclosed |