Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416535 | 1.00 | TGM2 (0.55) | TGM2HDAC1HDAC2HDAC3MAPK1 | |
| Hydrochloric Acid SCHEMBL29278808 | 0.98 | TGM2 (0.53) | TGM2HDAC1HDAC2HDAC3MAPK1 | |
| SCHEMBL31228347 | 0.86 | TGM2 (0.65) | TGM2PTPN1PTPN11 | |
| SCHEMBL613090 | 0.86 | TGM2 (0.65) | TGM2PTPN1PTPN11 | |
| SCHEMBL16096123 | 0.85 | TGM2 (0.47) | TGM2HDAC1HDAC2HDAC3MAPK1 | |
| SCHEMBL9132645 | 0.82 | HDAC1 (0.56) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL10024764 | 0.82 | PTPN1 (0.51) | TGM2PTPN1PTPN11NPC1RAB9A | |
| SCHEMBL23653363 | 0.81 | TGM2 (0.55) | TGM2PTPN1PTPN11 | |
| SCHEMBL1379801 | 0.81 | ALDH1A1 (0.64) | TGM2PTPN1PTPN11NPC1RAB9A | |
| SCHEMBL12965010 | 0.80 | HDAC3 (0.50) | HDAC1HDAC2HDAC3MAPK1NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090509-A | Solution for making photoconductive layers and their electrophotographical manufacturing in CRTs | ORION ELECTRIC CO., LTD. (KR) | 2000-07-18 | — | — | US | claimed |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| CN-114106407-B | Blood perfusion adsorbent and preparation method thereof | 泉州师范学院 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023143402-A1 | STEROID COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| US-20230202980-A1 | N-(2-Aminophenyl)-Prop-2-Enamide Derivatives, and Uses Thereof in the Treatment of Cancer | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230202980-A1 | N-(2-Aminophenyl)-Prop-2-Enamide Derivatives, and Uses Thereof in the Treatment of Cancer | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2023-06-29 | — | — | US | disclosed |
| CN-111918881-B | Novel photocrosslinkable alginic acid derivative | 持田制药株式会社 | 2022-08-12 | — | — | CN | disclosed |
| EP-4021906-A1 | N-(2-AMINOPHENYL)-PROP-2-ENAMIDE DERIVATIVES, AND USES THEREOF IN THE TREATMENT OF CANCER | National University of Singapore (SG) | 2022-07-06 | — | — | EP | disclosed |
| CN-114106407-A | Blood perfusion adsorbent and preparation method thereof | 泉州师范学院 | 2022-03-01 | — | — | CN | disclosed |
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |
| WO-1998024111-A1 | A SOLUTION FOR MAKING PHOTOCONDUCTIVE LAYERS AND THEIR ELECTROPHOTOGRAPHICAL MANUFACTURING IN CRTS | ORION ELECTRIC CO., LTD. (KR) | 1998-06-04 | — | — | WO | disclosed |
| US-5053494-A | FIBER REACTIVE POLYAZO DYE HAVING TWO VINYLSULFONE TYPE REACTIVE GROUPS THROUGH TRIAZINYL BRIDGING GROUP | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0266774-B1 | POLYAZO COMPOUND HAVING TWO VINYLSULFONE TYPE FIBER REACTIVE GROUPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0330239-A2 | Photosensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0266774-A1 | Polyazo compound having two vinylsulfone type fiber reactive groups | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-05-11 | — | — | EP | disclosed |
| US-4254143-A | PARACITICIDES; LIVER FLUKES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-03 | — | — | US | disclosed |
| US-4018814-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | disclosed |
| US-4013676-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3996247-A | ANTHELMINTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202980-A1 | N-(2-Aminophenyl)-Prop-2-Enamide Derivatives, and Uses Thereof in the Treatment of Cancer | SALL4, GLI2, GLI1 | TGM2 1519/4885HDAC1 1366/4885HDAC2 1247/4885 |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | TGM2 3856/4885HDAC1 299/4885HDAC2 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.