Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | HTR6 | P50406 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027348 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL12610324 | 0.82 | ALDH1A1 (0.71) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL9732946 | 0.81 | KMT2A (0.79) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| Diethyltryptamine SCHEMBL517713 | 0.78 | HTR1A (1.00) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| Diethyltryptamine SCHEMBL22462319 | 0.77 | HTR1A (0.97) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL22619123 | 0.76 | ALDH1A1 (0.73) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL22027268 | 0.75 | HTR2A (1.00) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| Tryptamine SCHEMBL22800107 | 0.74 | HTR2A (0.77) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| Gramine SCHEMBL63578 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| Gramine SCHEMBL29351803 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299035-B2 | 10a-azalide compound having 4-membered ring structure | TAISHO PHARMACEUTUCAL CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20110152239-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| EP-2287173-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152239-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | ELOVL3, ELOVL5, SCD5 | ALDH1A1 3050/4885KDM4E 60/4885MEN1 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.