Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22808735 | 0.84 | CYP3A4 (0.42) | ALDH1A1HSD17B10CFTRKMT2AKDM4E | |
| SCHEMBL28996258 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CFTRKMT2AKDM4E | |
| SCHEMBL8568940 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CFTRKMT2AKDM4E | |
| SCHEMBL2635055 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CFTRKMT2AKDM4E | |
| SCHEMBL1427758 | 0.81 | ALDH1A1 (0.37) | ALDH1A1HSD17B10CFTRKMT2AKDM4E | |
| SCHEMBL28261816 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CFTRKMT2AKDM4E | |
| SCHEMBL7443221 | 0.79 | POLB (0.47) | ALDH1A1KMT2AKDM4EPOLBCA1 | |
| SCHEMBL9666407 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2ATSHRNPC1MAPK1 | |
| SCHEMBL18177743 | 0.79 | GABRA1 (0.47) | ALDH1A1KMT2APOLBCA1CA2 | |
| SCHEMBL6404524 | 0.79 | POLB (0.47) | ALDH1A1KMT2AKDM4EPOLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268510-A | DEMETHANIZATION, METABOLISM, RUMEN | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | disclosed |
| EP-0010348-A1 | Heterocyclic trichloromethyl derivatives, process for their preparation and their use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | disclosed |