SCHEMBL28996258

SCHEMBL28996258

COC(=O)C(C(=O)OC)c1ccccc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
HSD17B10 Q99714 3/20 0.48
CFTR P13569 1/20 0.48
KMT2A Q03164 2/20 0.46
MMP8 P22894 1/20 0.40
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
ADRA2B P18089 1/20 0.38
PTGS1 P23219 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869693 0.91 ALDH1A1 (0.47) ALDH1A1HSD17B10CFTRKMT2AMMP8
SCHEMBL6074907 0.85 ALDH1A1 (0.54) ALDH1A1HSD17B10KMT2AMMP8TDP1
SCHEMBL2635055 0.83 ALDH1A1 (0.47) ALDH1A1HSD17B10CFTRKMT2AHDAC3
SCHEMBL11330367 0.83 ALDH1A1 (0.47) ALDH1A1HSD17B10CFTRKMT2AHDAC3
SCHEMBL8568940 0.83 ALDH1A1 (0.47) ALDH1A1HSD17B10CFTRKMT2AHDAC3
SCHEMBL28261816 0.81 ALDH1A1 (0.46) ALDH1A1HSD17B10CFTRKMT2AHDAC3
SCHEMBL3414451 0.80 LMNA (0.43) ALDH1A1HSD17B10CFTRKMT2A
SCHEMBL11515749 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10CFTRKMT2AHDAC3
SCHEMBL27901422 0.78 ALDH1A1 (0.57) ALDH1A1KMT2ATSHR
SCHEMBL29907231 0.77 ALDH1A1 (0.60) ALDH1A1HSD17B10CFTRKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082213-A Preparation method of 5-cyanoindole 苏州永健生物医药有限公司 2023-05-09 CN claimed
CN-116082213-A Preparation method of 5-cyanoindole 苏州永健生物医药有限公司 2023-05-09 CN disclosed
CN-116082213-A Preparation method of 5-cyanoindole 苏州永健生物医药有限公司 2023-05-09 CN disclosed