Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | RNF4 | P78317 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571013 | 0.97 | SLC18A3 (0.44) | SLC18A3KCNA5MMP1MMP9MMP13 | |
| SCHEMBL11341305 | 0.85 | SIGMAR1 (0.45) | TRPM8SIGMAR1MAPT | |
| SCHEMBL11347000 | 0.84 | SIGMAR1 (0.41) | TRPM8SIGMAR1MAPT | |
| SCHEMBL11334204 | 0.82 | SLC18A3 (0.52) | SLC18A3CHRM2CHRM3SIGMAR1OPRM1 | |
| SCHEMBL11330424 | 0.82 | SLC18A3 (0.43) | SLC18A3MAPK1CHRM2CHRM3SIGMAR1 | |
| SCHEMBL11454737 | 0.82 | SIGMAR1 (0.43) | TRPM8CHRM2CHRM3SIGMAR1OPRM1 | |
| SCHEMBL11350705 | 0.81 | ALDH1A1 (0.45) | TRPM8CHRM2CHRM3SIGMAR1OPRM1 | |
| SCHEMBL11572457 | 0.81 | TSHR (0.41) | TRPM8SIGMAR1MAPT | |
| SCHEMBL11595372 | 0.79 | SLC18A3 (0.50) | SLC18A3CHRM2CHRM3SIGMAR1OPRM1 | |
| SCHEMBL11337129 | 0.79 | MEN1 (0.40) | SLC18A3TRPM8SIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |