Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489559 | 1.00 | BACE1 (0.61) | BACE1LMNATSHRALDH1A1MAPT | |
| SCHEMBL9464209 | 0.88 | BACE1 (0.62) | BACE1LMNATSHRALDH1A1MAPT | |
| SCHEMBL9464207 | 0.88 | BACE1 (0.62) | BACE1LMNATSHRALDH1A1MAPT | |
| SCHEMBL69553 | 0.87 | BACE1 (0.60) | BACE1LMNATSHRALDH1A1MAPT | |
| SCHEMBL69552 | 0.87 | BACE1 (0.60) | BACE1LMNATSHRALDH1A1MAPT | |
| SCHEMBL6799876 | 0.86 | TRPA1 (0.52) | BACE1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL6799880 | 0.86 | TRPA1 (0.52) | BACE1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL23618911 | 0.86 | BACE1 (0.61) | BACE1LMNATSHRALDH1A1MAPT | |
| SCHEMBL30977151 | 0.86 | BACE1 (0.61) | BACE1LMNATSHRALDH1A1MAPT | |
| SCHEMBL10372644 | 0.86 | BACE1 (0.61) | BACE1LMNATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150269-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2024-05-09 | — | — | US | disclosed |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-11795132-B2 | Application of metal hydride/palladium compound system in preparation of 1,3-dicarbonyl compound in cascade reaction of electron-deficient alkene compound | SOOCHOW UNIVERSITY (CN) | 2023-10-24 | — | — | US | disclosed |
| US-11795132-B2 | Application of metal hydride/palladium compound system in preparation of 1,3-dicarbonyl compound in cascade reaction of electron-deficient alkene compound | SOOCHOW UNIVERSITY (CN) | 2023-10-24 | — | — | US | disclosed |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| EP-4157811-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | McMaster University (CA) | 2023-04-05 | — | — | EP | disclosed |
| US-11512034-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2022-11-29 | — | — | US | disclosed |
| WO-2000066676-A1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000066675-A1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, HIGH EXTINCTION, PHOTOSTABLE HYDROXYPHENYL-s-TRIAZINE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SPECIALTY CHEMICALS HOLDING INC. (DE) | 2000-11-09 | — | — | WO | disclosed |
| EP-0389432-A2 | Hindered amine derivatives of triazine and hexahydrotriazine | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| US-4886610-A | EXTREME PRESSURE LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |
| US-4830770-A | EXTREME PRESSURE LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4808755-A | EXTREME PRESSURE LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| US-4772405-A | ANTIWEAR, EXTREME PRESSURE AND ANTIOXIDANT ADDITIVE FOR SYNTHETIC AND MINERAL LUBRICANTS, ELASTOMERS, HYDRAULIC FLUIDS | CIBA-GEIGY CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4732691-A | HYDROXY AMINES | CIBA-GEIGY CORPORATION (US) | 1988-03-22 | — | — | US | disclosed |
| US-4556714-A | LIGHT STABILIZER FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1985-12-03 | — | — | US | disclosed |
| US-4532279-A | Polyalkylpiperidine esters of aliphatic tetracarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1985-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | BACE1 2351/4885LMNA 3504/4885TSHR 1755/4885 |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | BACE1 2351/4885LMNA 3504/4885TSHR 1755/4885 |
| US-11512034-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | BACE1 2351/4885LMNA 3504/4885TSHR 1755/4885 |
| US-20240150269-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | BACE1 1851/4885LMNA 3620/4885TSHR 1973/4885 |
| US-11795132-B2 | Application of metal hydride/palladium compound system in preparation of 1,3-dicarbonyl compound in cascade reaction of electron-deficient alkene compound | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HVCN1, HRH4 | BACE1 3317/4885LMNA 3229/4885TSHR 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.