Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571430 | 1.00 | KLK5 (0.57) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL1133288 | 1.00 | KLK5 (0.57) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL5887534 | 0.93 | CTSS (0.53) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL5887530 | 0.93 | CTSS (0.53) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL1111226 | 0.90 | CTSS (0.50) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL1111230 | 0.90 | CTSS (0.50) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL5887200 | 0.88 | CTSS (0.49) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL5887203 | 0.88 | CTSS (0.49) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL12035376 | 0.88 | KLK5 (0.58) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL16232664 | 0.88 | KLK5 (0.58) | KLK5CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109021003-B | Preparation method of vinyl silicon/germanium/stannane derivative | 华侨大学 | 2021-06-01 | — | — | CN | claimed |
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| CN-115710286-B | Preparation method of cis-styryl boron derivative | 华侨大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-115710286-A | Preparation method of cis-styrylboron derivative | 华侨大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-110003271-B | Process for producing aromatic compound | 住友化学株式会社 | 2022-05-03 | — | — | CN | disclosed |
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| CN-109021003-B | Preparation method of vinyl silicon/germanium/stannane derivative | 华侨大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-108368142-B | Method for producing aromatic compound and palladium complex | 住友化学株式会社 | 2021-02-19 | — | — | CN | disclosed |
| CN-110437068-B | Preparation method of aromatic methylation | 武汉大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-110437068-A | A kind of preparation method of aromatic hydrocarbons methylation | UNIV WUHAN | 2019-11-12 | — | — | CN | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-20030162950-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-28 | — | — | US | disclosed |
| EP-1306131-A2 | Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-02 | — | — | EP | disclosed |
| CN-1092624-C | Method for removing heavy metals | ZAMBON SPA (IT) | 2002-10-16 | — | — | CN | disclosed |
| CN-1351592-A | Acyl derivatives for the treatment of VLA-4 related diseases | ELAN PHARM INC (US) | 2002-05-29 | — | — | CN | disclosed |
| EP-1044215-A1 | ANTI-INFLAMMATORY PHENYLALANINE DERIVATIVES | CELLTECH THERAPEUTICS LIMITED (GB) | 2000-10-18 | — | — | EP | disclosed |
| CN-1255912-A | Process for removal of heavy metals | ZAMBON SPA (IT) | 2000-06-07 | — | — | CN | disclosed |
| WO-1999035163-A1 | PHENYLALANINE DERIVATIVES | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162950-A1 | Coupling catalyst and process using the same | NOD1, PYM1, C9 | KLK5 4351/4885CTSS 3882/4885CTSK 4109/4885 |
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | DDT, DRD1, DRD2 | KLK5 4117/4885CTSS 2828/4885CTSK 2690/4885 |
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | KLK5 4410/4885CTSS 1702/4885CTSK 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.