Phosphoric Acid

Phosphoric Acid

SCHEMBL1133295

CC#N.O=P(O)(O)O.O=P(O)(O)O.[KH]

nearest known ligand 0.40

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.40
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28275596 1.00 CA2 (0.40) CA2LMNA
Phosphoric Acid SCHEMBL182596 1.00
Phosphoric Acid SCHEMBL8505699 0.96 CA2 (0.43) CA2LMNA
Phosphoric Acid SCHEMBL7601322 0.96 CA2 (0.43) CA2LMNA
Phosphoric Acid SCHEMBL854955 0.96
Phosphoric Acid SCHEMBL6036466 0.96 CA2 (0.43) CA2LMNA
Phosphoric Acid SCHEMBL6383668 0.96 CA2 (0.43) CA2LMNA
Phosphoric Acid SCHEMBL17555384 0.96 CA2 (0.43) CA2LMNA
Phosphoric Acid SCHEMBL675651 0.96
Phosphoric Acid SCHEMBL4453244 0.96 CA2 (0.43) CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993800-B2 Process for producing optically active α-methylcysteine derivative KANEKA CORPORATION (JP) 2015-03-31 US disclosed
US-20130261331-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-METHYLCYSTEINE DERIVATIVE KANEKA CORP (JP) 2013-10-03 US disclosed
EP-2287152-A2 Process for producing optically active alpha-methylcysteine derivative KANEKA CORPORATION (JP) 2011-02-23 EP disclosed
US-20100197934-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-METHYLCYSTEINE DERIVATIVE KANEKA CORPORATION (JP) 2010-08-05 US disclosed
US-20060105435-A1 Process for producing optically active alpha-methylcysteine derivative KANEKA CORPORATION (JP) 2006-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197934-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-METHYLCYSTEINE DERIVATIVE AHCY, CTH, BHMT CA2 457/4885LMNA 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.