Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328461 | 0.79 | MAPT (0.39) | HPGDSMN1; SMN2HSD17B10MAPTTSHR | |
| SCHEMBL5013542 | 0.76 | GABRA2 (0.54) | HPGDHSD17B10MAPTNPSR1ALDH1A1 | |
| SCHEMBL11330465 | 0.75 | ALDH1A1 (0.64) | HPGDSMN1; SMN2HSD17B10MAPTTSHR | |
| SCHEMBL20518799 | 0.74 | ALDH1A1 (0.52) | SMN1; SMN2MAPTTSHRALDH1A1KDM4E | |
| SCHEMBL11314056 | 0.74 | L3MBTL1 (0.40) | HPGDSMN1; SMN2HSD17B10MAPTTSHR | |
| SCHEMBL17863722 | 0.73 | SMN1; SMN2 (0.36) | HPGDSMN1; SMN2HSD17B10MAPTTSHR | |
| SCHEMBL11318315 | 0.73 | ALDH1A1 (0.61) | HPGDSMN1; SMN2HSD17B10MAPTTSHR | |
| SCHEMBL1314260 | 0.72 | GABRA2 (0.51) | HPGDSMN1; SMN2HSD17B10MAPTALDH1A1 | |
| SCHEMBL5015641 | 0.71 | PTGS2 (0.43) | HPGDHSD17B10MAPTALDH1A1RAB9A | |
| SCHEMBL496791 | 0.69 | KDM4E (0.71) | HPGDSMN1; SMN2HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267339-A | ANTIDIABETIC AGENTS | PLANTEX LTD. (IL) | 1981-05-12 | — | — | US | disclosed |
| US-4137320-A | Pharmaceutical compositions containing imidazo(2,1-b)thiazoles and process for reducing blood sugar levels therewith | PLANTEX, LTD. (IL) | 1979-01-30 | — | — | US | disclosed |