Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323481 | 0.84 | GAA (0.52) | MAPTHPGDRAB9AKDM4ENPC1 | |
| SCHEMBL11314056 | 0.82 | L3MBTL1 (0.40) | MAPTHPGDSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL17863723 | 0.81 | RAB9A (0.36) | MAPTSMN1; SMN2TSHRNPSR1USP2 | |
| SCHEMBL11314026 | 0.81 | RAB9A (0.39) | MAPTHPGDSMN1; SMN2TSHRUSP2 | |
| SCHEMBL17863722 | 0.81 | SMN1; SMN2 (0.36) | MAPTHPGDSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL11333368 | 0.79 | HPGD (0.48) | MAPTHPGDSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL11319468 | 0.74 | ALOX15 (0.57) | MAPTHPGDSMN1; SMN2TSHRRAB9A | |
| SCHEMBL20518799 | 0.73 | ALDH1A1 (0.52) | MAPTSMN1; SMN2TSHRRAB9AKDM4E | |
| SCHEMBL17863721 | 0.72 | CYP19A1 (0.42) | MAPTHPGDNPSR1KDM4EMEN1 | |
| SCHEMBL11314005 | 0.70 | GAA (0.50) | MAPTHPGDRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267339-A | ANTIDIABETIC AGENTS | PLANTEX LTD. (IL) | 1981-05-12 | — | — | US | claimed |
| US-4137320-A | Pharmaceutical compositions containing imidazo(2,1-b)thiazoles and process for reducing blood sugar levels therewith | PLANTEX, LTD. (IL) | 1979-01-30 | — | — | US | claimed |
| US-9512144-B2 | Imidazothiazole sufonamides as nematicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20160176898-A1 | IMIDAZOTHIAZOLE SUFONAMIDES AS NEMATICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-23 | — | — | US | disclosed |
| US-4267339-A | ANTIDIABETIC AGENTS | PLANTEX LTD. (IL) | 1981-05-12 | — | — | US | disclosed |
| US-4137320-A | Pharmaceutical compositions containing imidazo(2,1-b)thiazoles and process for reducing blood sugar levels therewith | PLANTEX, LTD. (IL) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176898-A1 | IMIDAZOTHIAZOLE SUFONAMIDES AS NEMATICIDES | NISCH, TST, SULT1E1 | MAPT 2089/4885HPGD 1689/4885SMN1; SMN2 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.