Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19540906 | 0.90 | SIRT2 (0.52) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL17683316 | 0.87 | SIRT2 (0.50) | SIRT2CYP4F2CYP4A11HDAC1HDAC6 | |
| SCHEMBL1410879 | 0.86 | SIRT2 (0.52) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL28655132 | 0.86 | SLC7A5 (0.57) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL7716761 | 0.85 | SIRT2 (0.51) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL15504971 | 0.85 | SIRT2 (0.51) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL5043214 | 0.85 | LOXL2 (0.57) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL13104077 | 0.85 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1TDP1MAPT | |
| SCHEMBL13577590 | 0.85 | CYP1A2 (0.54) | CYP4F2CYP4A11ALDH1A1KDM4ELMNA | |
| SCHEMBL3295184 | 0.85 | SIRT2 (0.51) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-10-21 | — | — | US | disclosed |
| US-8012964-B2 | 9-substituted 8-oxoadenine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20070190071-A1 | 9-Substituted 8-oxoadenine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190071-A1 | 9-Substituted 8-oxoadenine compound | IFNAR1, IL5, IFNG | SIRT2 2681/4885BRD4 1255/4885CYP4F2 1911/4885 |
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | SIRT2 4062/4885BRD4 1279/4885CYP4F2 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.