Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377610 | 0.77 | SMN1; SMN2 (0.34) | OPRK1CYP26A1OPRD1 | |
| SCHEMBL11335494 | 0.76 | CYP19A1 (0.40) | MGLLFAAHCYP19A1KDM4EOPRK1 | |
| SCHEMBL28381059 | 0.72 | MC4R (0.34) | OPRK1ALDH1A1OPRD1LMNA | |
| SCHEMBL11337559 | 0.71 | MGLL (0.35) | MGLLFAAHCYP19A1KMT2AALDH1A1 | |
| SCHEMBL10514880 | 0.71 | MGLL (0.35) | MGLLFAAHCYP19A1KMT2AALDH1A1 | |
| SCHEMBL28887530 | 0.70 | ACHE (0.36) | OPRK1OPRD1 | |
| SCHEMBL11330557 | 0.69 | CYP19A1 (0.40) | CYP19A1KDM4EOPRK1KMT2AALDH1A1 | |
| SCHEMBL1606039 | 0.69 | CYP17A1 (0.53) | CYP19A1OPRK1KMT2AALDH1A1MEN1 | |
| SCHEMBL8865912 | 0.69 | CYP19A1 (0.40) | MGLLFAAHCYP19A1KDM4EOPRK1 | |
| SCHEMBL11332342 | 0.69 | ALDH1A1 (0.47) | MGLLFAAHCYP19A1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000373-B1 | IMIDAZOLE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULANTS OR PLANT PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0000373-A1 | Imidazole carboxylic acids and derivatives thereof, process for their preparation and their use as plant growth regulants or plant protection agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-24 | — | — | EP | disclosed |