Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706183 | 0.85 | LMNA (0.44) | KDM4ELMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL28705125 | 0.83 | ALDH1A1 (0.51) | KDM4ELMNAALDH1A1TDP1OPRD1 | |
| SCHEMBL28935871 | 0.80 | KDM4C (0.46) | KDM4ELMNAALDH1A1OPRD1OPRK1 | |
| SCHEMBL11335498 | 0.76 | MGLL (0.38) | CYP19A1KDM4EFAAHMGLLLMNA | |
| SCHEMBL28182708 | 0.74 | PTGS2 (0.34) | — | |
| SCHEMBL1431164 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1OPRD1OPRK1 | |
| SCHEMBL8865912 | 0.72 | CYP19A1 (0.40) | CYP19A1KDM4EFAAHMGLLALDH1A1 | |
| SCHEMBL11330557 | 0.72 | CYP19A1 (0.40) | CYP19A1KDM4EALDH1A1TDP1OPRD1 | |
| SCHEMBL28416467 | 0.71 | FPR2 (0.43) | KDM4ELMNAALDH1A1 | |
| SCHEMBL20591026 | 0.71 | TTR (0.43) | ALDH1A1TDP1OPRD1KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000373-B1 | IMIDAZOLE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULANTS OR PLANT PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-4182624-A | FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
| EP-0000373-A1 | Imidazole carboxylic acids and derivatives thereof, process for their preparation and their use as plant growth regulants or plant protection agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-24 | — | — | EP | disclosed |