Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533466 | 0.89 | LMNA (0.38) | LMNATDP1TP53TSHRALDH1A1 | |
| SCHEMBL11337559 | 0.85 | MGLL (0.35) | MGLLLMNATDP1CACNA1HCACNA2D1 | |
| SCHEMBL10391240 | 0.75 | MAPK1 (0.44) | LMNATP53TSHRALDH1A1MAPK1 | |
| SCHEMBL11332342 | 0.71 | ALDH1A1 (0.47) | MGLLLMNATDP1ALDH1A1MAPK1 | |
| SCHEMBL11335498 | 0.71 | MGLL (0.38) | MGLLLMNATDP1TP53ALDH1A1 | |
| SCHEMBL11493710 | 0.67 | PKM (0.50) | LMNATDP1TSHRALDH1A1MAPK1 | |
| SCHEMBL11325136 | 0.66 | ALDH1A1 (0.44) | MGLLLMNATDP1ALDH1A1MAPK1 | |
| SCHEMBL11565546 | 0.65 | ALDH1A1 (0.44) | LMNATDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL11325403 | 0.65 | MAPK1 (0.45) | LMNATP53TSHRALDH1A1MAPK1 | |
| SCHEMBL11374737 | 0.63 | ALDH1A1 (0.44) | MGLLLMNATDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |