2,4-Dichlorophenol

2,4-Dichlorophenol

SCHEMBL16619805

COC.Oc1ccc(Cl)cc1Cl

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.81
TSHR P16473 3/20 0.81
CYP3A4 P08684 4/20 0.52
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 1/20 0.52
HPGD P15428 5/20 0.50
HSP90AA1 P07900 3/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
HSPA5 P11021 2/20 0.50
NR1I2 O75469 1/20 0.50
TTR P02766 1/20 0.50
PGR P06401 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
CBR1 P16152 1/20 0.50
TBXA2R P21731 1/20 0.50
SLC6A2 P23975 1/20 0.50
AGTR1 P30556 1/20 0.50
SLC6A3 Q01959 1/20 0.50
ALOX15 P16050 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenol SCHEMBL28184971 0.90 HSD17B10 (0.90) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL77936 0.90
2,4-Dichlorophenol SCHEMBL30084868 0.90
2,4-Dichlorophenol SCHEMBL30396784 0.90
2,4-Dichlorophenol SCHEMBL8526331 0.87 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL28226615 0.87 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL27937117 0.87 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL7394579 0.87 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL29404519 0.87 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL28226476 0.87 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3077353-B1 PROCESS FOR PURIFYING 2,5-DICHLOROPHENOL BASF SE (DE) 2019-02-06 EP disclosed
US-10093607-B2 Selective hydrolysis and alcoholysis of chlorinated benzenes BASF SE (DE) 2018-10-09 US disclosed
EP-3052462-B1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2018-08-22 EP disclosed
US-9701604-B2 Process for purifying 2,5-dichlorophenol BASF SE (DE) 2017-07-11 US disclosed
US-9643909-B2 Process for hydrolyzing 1,2,4-trihalobenzene BASF SE (DE) 2017-05-09 US disclosed
EP-3052463-B1 PROCESS FOR HYDROLYZING 1,2,4-TRIHALOBENZENE BASF SE (DE) 2017-03-01 EP disclosed
US-20160304425-A1 Process for Purifying 2,5-Dichlorophenol BASF SE (DE) 2016-10-20 US disclosed
EP-3077353-A1 PROCESS FOR PURIFYING 2,5-DICHLOROPHENOL BASF SE (DE) 2016-10-12 EP disclosed
US-20160289157-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2016-10-06 US disclosed
US-20160251294-A1 Process for Hydrolyzing 1,2,4-trihalobenzene BASF SE (DE) 2016-09-01 US disclosed
EP-3052463-A1 PROCESS FOR HYDROLYZING 1,2,4-TRIHALOBENZENE BASF SE (DE) 2016-08-10 EP disclosed
EP-3052462-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2016-08-10 EP disclosed
WO-2015082415-A1 PROCESS FOR PURIFYING 2,5-DICHLOROPHENOL BASF SE (DE) 2015-06-11 WO disclosed
WO-2015049360-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2015-04-09 WO disclosed
WO-2015049160-A1 PROCESS FOR HYDROLYZING 1,2,4-TRIHALOBENZENE BASF SE (DE) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289157-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES ADH1C, ADH1A, ADH5 HSD17B10 467/4885TSHR 408/4885CYP3A4 13/4885
US-20160304425-A1 Process for Purifying 2,5-Dichlorophenol HDHD5, DCPS, RCC2 HSD17B10 240/4885TSHR 2069/4885CYP3A4 122/4885
US-10093607-B2 Selective hydrolysis and alcoholysis of chlorinated benzenes ADH1C, ADH1A, ADH5 HSD17B10 484/4885TSHR 386/4885CYP3A4 11/4885
US-20160251294-A1 Process for Hydrolyzing 1,2,4-trihalobenzene XDH, TYR, TH HSD17B10 287/4885TSHR 824/4885CYP3A4 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.