SCHEMBL1133590

SCHEMBL1133590

CC(C)c1c(F)c(C#N)c(C#N)c(F)c1C(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRPV4 Q9HBA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21410256 0.87 KDM4E (0.30) TRPV4
SCHEMBL2723747 0.85 — —
SCHEMBL18135474 0.84 TRPV4 (0.31) TRPV4
SCHEMBL21410740 0.82 TRPV4 (0.30) TRPV4
SCHEMBL11063464 0.82 TRPV4 (0.30) TRPV4
SCHEMBL18348918 0.77 TSHR (0.33) —
SCHEMBL26382425 0.75 — —
SCHEMBL13058558 0.73 HTT (0.31) —
SCHEMBL13058553 0.73 TRPV4 (0.38) TRPV4
SCHEMBL12304964 0.73 KDM4E (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110168543-A1 Microwave-Assisted Synthesis of Perfluorophthalocyanine Molecules NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2011-07-14 — — US claimed
US-20110172437-A1 Perfluorophthalocyanine Molecules and Methods of Synthesis NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2011-07-14 — — US claimed
EP-2285909-A1 PERFLUOROPHTHALOCYANINE MOLECULES AND METHODS FOR SYNTHESIS New Jersey Institute of Technology (US) 2011-02-23 — — EP claimed
EP-2285907-A1 MICROWAVE-ASSISTED SYNTHESIS OF PERFLUOROPHTHALOCYANINE MOLECULES New Jersey Institute of Technology (US) 2011-02-23 — — EP claimed
WO-2009148693-A1 PERFLUOROPHTHALOCYANINE MOLECULES AND METHODS FOR SYNTHESIS NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2009-12-10 — — WO claimed
WO-2009139973-A1 MICROWAVE-ASSISTED SYNTHESIS OF PERFLUOROPHTHALOCYANINE MOLECULES NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2009-11-19 — — WO claimed
US-10942142-B2 Methods and apparatus for analyte detection using fluorinated phthalocyanines SETON HALL UNIVERSITY (US) 2021-03-09 — — US disclosed
EP-3652527-A1 METHODS AND APPARATUS FOR DETECTION OF ANALYTES USING FLUORINATED PHTHALOCYANINES Universiteit Antwerpen (BE) 2020-05-20 — — EP disclosed
WO-2019012114-A1 METHODS AND APPARATUS FOR DETECTION OF ANALYTES USING FLUORINATED PHTHALOCYANINES UNIVERSITEIT ANTWERPEN (BE) 2019-01-17 — — WO disclosed
US-20190017955-A1 METHODS AND APPARATUS FOR ANALYTE DETECTION USING FLUORINATED PHTHALOCYANINES SETON HALL UNIVERSITY (US) 2019-01-17 — — US disclosed
US-20150368194-A1 System and Method for Fluoralkylated Fluorophthalocyanines with Aggregating Properties and Catalytic Driven Pathway for Oxidizing Thiols GORUN SERGIU M (US) 2015-12-24 — — US disclosed
US-20150315137-A1 System and Method for Fluoroalkylated Fluorophthalocyanines With Aggregating Properties and Catalytic Driven Pathway for Oxidizing Thiols NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2015-11-05 — — US disclosed
US-8349457-B2 Thin film applications of perfluoroisopropyl-substituted perfluorophthalocyanines NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2013-01-08 — — US disclosed
US-20110168543-A1 Microwave-Assisted Synthesis of Perfluorophthalocyanine Molecules NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2011-07-14 — — US disclosed
US-20110172437-A1 Perfluorophthalocyanine Molecules and Methods of Synthesis NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2011-07-14 — — US disclosed
EP-2285909-A1 PERFLUOROPHTHALOCYANINE MOLECULES AND METHODS FOR SYNTHESIS New Jersey Institute of Technology (US) 2011-02-23 — — EP disclosed
EP-2285907-A1 MICROWAVE-ASSISTED SYNTHESIS OF PERFLUOROPHTHALOCYANINE MOLECULES New Jersey Institute of Technology (US) 2011-02-23 — — EP disclosed
US-20100233845-A1 Thin Film Applications of Perfluoroisopropyl-Substituted Perfluorophthalocyanines NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2010-09-16 — — US disclosed
WO-2009148693-A1 PERFLUOROPHTHALOCYANINE MOLECULES AND METHODS FOR SYNTHESIS NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2009-12-10 — — WO disclosed
WO-2009139973-A1 MICROWAVE-ASSISTED SYNTHESIS OF PERFLUOROPHTHALOCYANINE MOLECULES NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2009-11-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190017955-A1 METHODS AND APPARATUS FOR ANALYTE DETECTION USING FLUORINATED PHTHALOCYANINES PPOX, LPO, PHPT1 TRPV4 933/4885
US-10942142-B2 Methods and apparatus for analyte detection using fluorinated phthalocyanines PPOX, LPO, PHPT1 TRPV4 933/4885
US-20110172437-A1 Perfluorophthalocyanine Molecules and Methods of Synthesis PICALM, PFKFB3, FOS TRPV4 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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