SCHEMBL1133665

SCHEMBL1133665

O=C(O)[C@H]1CN[C@H](C(=O)O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 1.00
CYP1A2 P05177 2/20 1.00
ALOX15 P16050 2/20 1.00
CYP2C19 P33261 2/20 1.00
SLC1A3 P43003 1/20 1.00
SLC1A2 P43004 1/20 1.00
SLC1A1 P43005 1/20 1.00
TSHR P16473 3/20 0.48
LMNA P02545 2/20 0.48
BLM P54132 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
PMP22 Q01453 2/20 0.48
RAB9A P51151 1/20 0.48
THRB P10828 1/20 0.48
ARG1 P05089 1/20 0.46
KDM4E B2RXH2 1/20 0.39
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2559376 1.00 CYP2D6 (1.00) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL8480461 1.00 CYP2D6 (1.00) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL12648650 1.00 CYP2D6 (1.00) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL8480462 1.00 CYP2D6 (1.00) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL2808482 1.00 CYP2D6 (1.00) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL2484170 1.00 CYP2D6 (1.00) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL542244 1.00 CYP2D6 (1.00) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL17743411 0.98 CYP2D6 (0.95) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL21402235 0.98 CYP2D6 (0.95) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL6652332 0.86 CYP2D6 (0.75) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118539490-A Multi-objective operation optimization control method and device for optical storage and charging micro-grid 电力规划总院有限公司 2024-08-23 CN claimed
US-20230136218-A1 METHODS AND COMPOSITIONS FOR TREATING ACUTE MYELOID LEUKEMIA PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-05-04 US claimed
WO-2023023538-A2 TREATING TISSUE INFLAMMATION MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2023-02-23 WO claimed
CN-114010633-A Application of glutamate transporter inhibitor in preparation of medicine for preventing and treating chronic hypoperfusion brain injury 廖儒佳 2022-02-08 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-8053585-B2 Protecting group for carboxylic acids that can be photolyzed by visible light CORNELL RESEARCH FOUNDATION, INC. (US) 2011-11-08 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
US-20070243519-A1 Protecting group for carboxylic acids that can be photolyzed by visible light CORNELL RESEARCH FOUNDATION, INC. (US) 2007-10-18 US claimed
WO-2000027374-B1 THE USE OF EXCITATORY AMINO ACID TRANSPORTER INHIBITORS TO REDUCE CNS WHITE MATTER INJURY LOEB HEALTH INST AT THE OTTAWA (CA) 2001-06-21 WO claimed
WO-2000027374-A2 THE USE OF EXCITATORY AMINO ACID TRANSPORTER INHIBITORS TO REDUCE CNS WHITE MATTER INJURY LOEB HEALTH INSTITUTE AT THE OTTAWA HOSPITAL (CA) 2000-05-18 WO claimed
US-5587509-A Caged caboxyl compounds and use thereof CORNELL RESEARCH FOUNDATION, INC. (US) 1996-12-24 US claimed
US-5430175-A Caged carboxyl compounds and use thereof CORNELL RESEARCH FOUNDATION, INC. (US) 1995-07-04 US claimed
WO-1995015305-A1 CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS CORNELL RESEARCH FOUNDATION, INC. (US) 1995-06-08 WO claimed
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES TRIPARTITE THERAPEUTICS INC. (TW) 2025-01-30 US disclosed
EP-4291301-B1 NON-INVASIVE CANCER TREATMENT SCIENTIA BIOTECH S L (ES) 2025-01-15 EP disclosed
CN-118539490-A Multi-objective operation optimization control method and device for optical storage and charging micro-grid 电力规划总院有限公司 2024-08-23 CN disclosed
US-5658782-A AN ISOLATED NUCLEIC ACID COMPRISING A NUCLEOTIDE SEQUENCE ENCODING A HUMAN EXCITATORY AMINO ACID TRANSPORTER PROTEIN; GENETIC ENGINEERING STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY A NON-PROFIT ORGANIZATION (US) 1997-08-19 US disclosed
WO-1997022251-A1 COMPOSITIONS FOR MODULATING INTRACELLULAR INOSITOL TRISPHOSPHATE CONCENTRATION AND USES THEREOF AYURCORE, INC. (US) 1997-06-26 WO disclosed
WO-1995015305-A1 CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS CORNELL RESEARCH FOUNDATION, INC. (US) 1995-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 CYP2D6 3808/4885CYP1A2 3261/4885ALOX15 914/4885
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES CD274, SELPLG, PDCD1LG2 CYP2D6 112/4885CYP1A2 592/4885ALOX15 836/4885
US-20070243519-A1 Protecting group for carboxylic acids that can be photolyzed by visible light CYBA, ALDH3A1, HCCS CYP2D6 630/4885CYP1A2 578/4885ALOX15 1049/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA CYP2D6 2307/4885CYP1A2 1104/4885ALOX15 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.