SCHEMBL907302

SCHEMBL907302

CC1=C(Cc2ccccc2)C(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
CALM1 P0DP23 1/20 0.41
DAO P14920 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40
ADORA1 P30542 2/20 0.38
MEN1 O00255 2/20 0.38
ADORA2A P29274 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ELANE P08246 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
TBXAS1 P24557 1/20 0.37
GAA P10253 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GSK3B P49841 1/20 0.37
IDH1 O75874 3/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133158 0.90 DAO (0.34) KMT2ADAOMEN1KDM4EMAPT
SCHEMBL168683 0.87 DAO (0.38) KMT2ADAOMEN1KDM4ETBXAS1
SCHEMBL27794707 0.83 MAOA (0.42) DAOMAPK1SMN1; SMN2HTT
SCHEMBL1132986 0.82 GSK3B (0.38) KMT2ADAOMAPK1MEN1KDM4E
SCHEMBL29150779 0.81 TP53 (0.43) KMT2ACALM1DAOCYP1A2CYP2C9
SCHEMBL27475055 0.78 LTA4H (0.44) KMT2ACALM1CYP1A2CYP2C9MAPK1
SCHEMBL10934636 0.77 CYP1A2 (0.51) KMT2ACALM1DAOCYP1A2CYP2C9
SCHEMBL22144488 0.77 CALM1 (0.41) KMT2ACALM1DAOCYP1A2CYP2C9
SCHEMBL6388542 0.77 CALM1 (0.41) KMT2ACALM1DAOCYP1A2CYP2C9
SCHEMBL1133697 0.76 ELANE (0.33) DAOELANEGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986703-A Preparation method of heat-resistant low-pressure-change damping rubber part for automobile 奇瑞汽车股份有限公司 2024-05-07 CN claimed
CN-114805959-B Pre-dispersed rubber auxiliary master batch, preparation method and application thereof 山东华聚高分子材料有限公司 2024-01-26 CN claimed
CN-117203276-A Rubber composition, rubber-metal composite, tire, hose and crawler belt 株式会社普利司通 2023-12-08 CN claimed
CN-117136142-A Rubber mixtures containing N, N' -dialkyl-p-phenylenediamine 朗盛德国有限责任公司 2023-11-28 CN claimed
CN-116102794-A High-modulus high-temperature-resistant dynamic shear fatigue rubber composition for tire and preparation method thereof 广东粤港澳大湾区黄埔材料研究院 2023-05-12 CN claimed
CN-112625371-B Damping sucker composite material and preparation method thereof 宁波柯林斯橡塑科技有限公司 2022-10-14 CN claimed
CN-114805959-A Pre-dispersed rubber auxiliary master batch, preparation method and application thereof 山东华聚高分子材料有限公司 2022-07-29 CN claimed
CN-113004588-B Aircraft tire tread composition and preparation method thereof 广东粤港澳大湾区黄埔材料研究院 2022-07-05 CN claimed
CN-112852027-B Rubber composition, preparation method of rubber and hourglass spring 比亚迪股份有限公司 2022-05-13 CN claimed
CN-114450335-A Rubber composition, rubber-metal composite, tire, conveyor belt, hose, and crawler belt 株式会社普利司通 2022-05-06 CN claimed
US-7549454-B2 radial medium truck tire; tensile strength, modulus retention, stiffness, fracture and tear resistance, reversion resistance; rubber and m-phenylenediamine bismaleimide and bis-(3-triethoxysilylpropyl)-tetrasulfide and 1,3-bis (citraconimido-methyl) benzene; no resorcinol resin, environmentally friendly THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-06-23 US claimed
CN-1995160-A Belt coat composition GOODYEAR TIRE & RUBBER (US) 2007-07-11 CN claimed
US-20070155876-A1 Belt coat composition THE GOODYEAR TIRE & RUBBER COMPANY 2007-07-05 US claimed
EP-1803769-A2 Belt coat composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-07-04 EP claimed
EP-1125976-B1 Chafer rubber composition, and heavy duty pneumatic tyre using the chafer rubber composition SUMITOMO RUBBER IND (JP) 2005-11-09 EP claimed
EP-1211282-B1 Rubber mix comprising expanded layer silicates CONITECH HOLDING GMBH (DE) 2004-12-01 EP claimed
US-20020122947-A1 Coating composition comprising a reactive diluent AKZO NOBEL N.V. (NL) 2002-09-05 US claimed
WO-2002034843-A1 COATING COMPOSITION COMPRISING A REACTIVE DILUENT AKZO NOBEL N.V. (NL) 2002-05-02 WO claimed
US-20010018944-A1 Blend including carbon black with given nitrogen adsorption specific surface area and 1,3-bis(citraconimidomethyl)benzene SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-09-06 US claimed
EP-1125976-A1 Chafer rubber composition, and heavy duty pneumatic tyre using the chafer rubber composition SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2001-08-22 EP claimed