Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571464 | 0.97 | CHRM2 (0.40) | CHRM2CHRM3ATMSLC18A3L3MBTL1 | |
| SCHEMBL26879524 | 0.72 | SLC18A3 (0.50) | ATMSLC18A3L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11338202 | 0.72 | CHRM3 (0.38) | CHRM2CHRM3ATMSLC18A3L3MBTL1 | |
| SCHEMBL20063747 | 0.69 | SLC18A3 (0.68) | SLC18A3L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL11571467 | 0.68 | PTGDR2 (0.38) | CHRM2CHRM3KDM4EALDH1A1TSPO | |
| SCHEMBL11350694 | 0.67 | L3MBTL1 (0.45) | CHRM2CHRM3SLC18A3L3MBTL1MEN1 | |
| SCHEMBL11331790 | 0.66 | ALDH1A1 (0.47) | CHRM2CHRM3ATMSLC18A3L3MBTL1 | |
| SCHEMBL11438363 | 0.66 | SLC18A3 (0.33) | CHRM2CHRM3SLC18A3LMNA | |
| SCHEMBL9455273 | 0.66 | GRIN2B (0.58) | SLC18A3L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL20506805 | 0.65 | SLC18A3 (0.49) | SLC18A3KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |