Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437822 | 0.71 | MEN1 (0.42) | CHRM2CHRM3 | |
| SCHEMBL11571464 | 0.69 | CHRM2 (0.40) | SLC18A3CHRM2CHRM3LMNA | |
| SCHEMBL11443856 | 0.68 | TACR1 (0.41) | CHRM2CHRM3 | |
| SCHEMBL11443857 | 0.68 | TACR1 (0.41) | CHRM2CHRM3 | |
| SCHEMBL11338199 | 0.66 | CHRM2 (0.39) | SLC18A3CHRM2CHRM3LMNA | |
| SCHEMBL11434729 | 0.65 | OPRM1 (0.50) | CHRM3 | |
| SCHEMBL11434731 | 0.65 | OPRM1 (0.50) | CHRM3 | |
| SCHEMBL11434897 | 0.64 | MEN1 (0.39) | SLC18A3CHRM2CHRM3 | |
| SCHEMBL11442252 | 0.63 | CHRM2 (0.36) | CHRM2CHRM3LMNA | |
| SCHEMBL11436730 | 0.62 | ALDH1A1 (0.38) | SLC18A3PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |