Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829303 | 0.84 | RECQL (0.71) | RECQLSMN1; SMN2TSHRCASP1SRD5A2 | |
| SCHEMBL5080596 | 0.84 | RECQL (0.71) | RECQLSMN1; SMN2TSHRCASP1SRD5A2 | |
| SCHEMBL30185351 | 0.82 | SMN1; SMN2 (0.71) | RECQLSMN1; SMN2TSHRCASP1SRD5A2 | |
| SCHEMBL195020 | 0.82 | SMN1; SMN2 (0.71) | RECQLSMN1; SMN2TSHRCASP1SRD5A2 | |
| SCHEMBL3050631 | 0.81 | RECQL (0.73) | RECQLSMN1; SMN2TSHRCASP1SRD5A2 | |
| SCHEMBL11224649 | 0.81 | ALDH1A1 (0.52) | RECQLSMN1; SMN2TSHRCASP1KDM4E | |
| SCHEMBL9749113 | 0.81 | ABCB11 (0.54) | RECQLSMN1; SMN2TSHRCASP1SRD5A2 | |
| SCHEMBL11624724 | 0.81 | RECQL (0.77) | RECQLSMN1; SMN2TSHRCASP1SRD5A2 | |
| SCHEMBL15628209 | 0.80 | ALOX15 (0.54) | RECQLSMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL11320848 | 0.79 | NR4A1 (0.56) | RECQLSMN1; SMN2SRD5A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254146-A | ANTIINFLAMMATORY AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1981-03-03 | — | — | US | disclosed |