SCHEMBL1133973

SCHEMBL1133973

O=Cc1ccc2cc(Br)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
CYP2A6 P11509 8/20 0.50
ERN1 O75460 2/20 0.47
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.41
PTPN1 P18031 1/20 0.41
ALDH1A3 P47895 1/20 0.39
NCEH1 Q6PIU2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30343618 1.00 ALDH1A1 (0.56) ALDH1A1CYP2A6ERN1KDM4EMEN1
SCHEMBL28952758 0.96 ALDH1A1 (0.52) ALDH1A1CYP2A6ERN1KDM4EMEN1
SCHEMBL28952320 0.96 ALDH1A1 (0.52) ALDH1A1CYP2A6ERN1KDM4EMEN1
SCHEMBL5783154 0.93 ALDH1A1 (0.54) ALDH1A1CYP2A6ERN1KDM4EMEN1
SCHEMBL11809502 0.90 ERN1 (0.56) ALDH1A1CYP2A6ERN1KDM4EMEN1
SCHEMBL977774 0.85 CYP2A6 (0.54) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL5930710 0.81 CYP2A6 (0.54) ALDH1A1CYP2A6KDM4EMEN1MAPT
SCHEMBL5930707 0.81 CYP2A6 (0.54) ALDH1A1CYP2A6KDM4EMEN1MAPT
SCHEMBL9883838 0.80 CYP2A6 (0.50) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL19182196 0.80 CYP2A6 (0.50) ALDH1A1CYP2A6KDM4EPTGS2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322165-A Near-infrared fluorescence probe imaging dynamic fluctuation of ferrous ions in hepatic fibrosis 镇江百单医疗生物科技有限公司 2022-11-11 CN claimed
EP-0116454-A2 Enhanced luminescent or luminometric assay NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-22 EP claimed
US-20260132295-A1 COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, METHOD FOR MANUFACTURING ARTICLE, AND ARTICLE AGC Inc. (JP) 2026-05-14 US disclosed
EP-4519384-B1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORP (US) 2026-04-29 EP disclosed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
EP-4652155-A1 AMYLOID TARGETING AGENTS Amydis, Inc. (US) 2025-11-26 EP disclosed
US-12478693-B2 Compositions and methods for detection of traumatic brain injury Amydis, Inc. (US) 2025-11-25 US disclosed
US-20250282723-A1 AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-11 US disclosed
US-20250213732-A1 PHOSPHATE COMPOUNDS FOR DETECTING NEUROLOGICAL DISORDERS AMYDIS INC (US) 2025-07-03 US disclosed
CN-120097938-A Synthesis method of 6- (piperazine-1-yl) -2-naphthaldehyde 上海泰坦科技股份有限公司 2025-06-06 CN disclosed
CN-119985995-A Compositions and methods for detecting traumatic brain injury 阿米达斯公司 2025-05-13 CN disclosed
EP-1472208-A1 NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2004-11-03 EP disclosed
EP-1423386-A1 THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-06-02 EP disclosed
EP-1385465-A2 HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF CANCER AND OTHER PROLIFERATIVE DISEASES Incyte San Diego, Inc. (US) 2004-02-04 EP disclosed
WO-2003066561-A1 NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2003-08-14 WO disclosed
WO-2003022842-A1 THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-03-20 WO disclosed
US-20020143182-A1 Heterocyclic derivatives for the treatment of cancer and other proliferative diseases INCYTE GENOMICS, INC. 2002-10-03 US disclosed
WO-2002072009-A2 HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF CANCER AND OTHER PROLIFERATIVE DISEASES MAXIA PHARMACEUTICALS, INC. (US) 2002-09-19 WO disclosed
US-5760048-A TREATMENT OF STROKE AND NERVOUS SYSTEM DISORDERS WARNER-LAMBERT COMPANY (US) 1998-06-02 US disclosed
US-5554767-A NERVOUS SYSTEM, CARDIOVASCULAR, AND BRAIN DISORDERS WARNER-LAMBERT COMPANY (US) 1996-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132295-A1 COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, METHOD FOR MANUFACTURING ARTICLE, AND ARTICLE MSR1, SEM1, ASH2L ALDH1A1 2834/4885CYP2A6 3611/4885ERN1 1555/4885
US-20020143182-A1 Heterocyclic derivatives for the treatment of cancer and other proliferative diseases CCNY, HRAS, AHR ALDH1A1 2952/4885CYP2A6 1095/4885ERN1 3905/4885
US-12478693-B2 Compositions and methods for detection of traumatic brain injury S100B, FABP7, CRYAB ALDH1A1 4102/4885CYP2A6 4482/4885ERN1 3255/4885
US-20250282723-A1 AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME CRYAA, IAPP, APP ALDH1A1 4174/4885CYP2A6 4681/4885ERN1 2177/4885
US-12590062-B2 PD-1/PD-L1 inhibitors CD274, PDCD1LG2, PDCD1 ALDH1A1 409/4885CYP2A6 1049/4885ERN1 1934/4885
US-20250213732-A1 PHOSPHATE COMPOUNDS FOR DETECTING NEUROLOGICAL DISORDERS PYGB, PSEN2, PSEN1 ALDH1A1 4527/4885CYP2A6 4539/4885ERN1 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.