Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.30 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536094 | 0.76 | KCNE1 (0.33) | TDP1MAP2K7S100A4CDC25ACDC25B | |
| SCHEMBL2540120 | 0.75 | ESR1 (0.35) | TDP1ESR1 | |
| SCHEMBL2537926 | 0.74 | ESR1 (0.33) | GAAHIF1AEPAS1ESR1 | |
| SCHEMBL8317551 | 0.73 | KEAP1 (0.30) | — | |
| SCHEMBL6623865 | 0.71 | PSIP1 (0.35) | TDP1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7849438 | 0.71 | ESR1 (0.33) | TDP1HTR6ESR1 | |
| SCHEMBL2460591 | 0.70 | TDP1 (0.37) | TDP1CNR2GAAAR | |
| SCHEMBL1077660 | 0.69 | KCNH2 (0.38) | TDP1CNR2 | |
| SCHEMBL2448855 | 0.69 | MAPT (0.37) | TDP1GAAESR1 | |
| SCHEMBL9800560 | 0.68 | KCNH2 (0.40) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268592-A | PYRAZOLONE MAGENTA COUPLER | CIBA-GEIGY AG (CH) | 1981-05-19 | — | — | US | disclosed |